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Small molecules comprising two mononucleotides, adenosine monophosphate (AMP) and nicotinamide mononucleotide (NMN); oxidized and reduced nicotinamide adenine dinucleotides in their unphosphorylated (NAD+ or NADH) and phosphorylated (NADP+ or NADPH) forms.
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Nicotinamide riboside malate is a salt of nicotinamide riboside and malic acid used as an NAD+ precursor and source of vitamin B3. It is employed in biochemical and cellular research to elevate cellular NAD+ levels, probe sirtuin-mediated pathways, and study metabolic and neuroprotective effects in vitro and in vivo models.
Orally active NAD+ precursor
Raises cellular NAD+ levels
Activates sirtuin pathways
Useful for metabolic and neuroprotection studies
Stable malate salt suitable for biochemical assays
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-Nicotinamide adenine dinucleotide (-NAD) is a ubiquitous biomolecule containing an adenylic acid and a nicotinamide-5AE-ribonucleotide group linked together by a pyrophosphate moiety. In NAD complexes the enzyme-cofactor interactions are highly conserved.
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